Contact Us

BioSynTech Malaysia Group Sdn Bhd
Revongen Corporation Center,
Level 17, Top Glove Tower,
No. 16, Persiaran Setia Dagang,
Setia Alam, Seksyen U13,
40170 Shah Alam, Selangor Darul Ehsan, Malaysia.


T : +6 03 8025 1603
F : +6 03 8025 1637
E :

On-Site COVID-19 RT-PCR Test Customer Care:
WhatsApp/Call: +6011 6122 0231

Social Media

New Small Molecules from MCE for October 2020

New Small Molecules from MCE for October 2020

MCE (MedChemExpress) provides a wide range of lifescience biochemicals, including more than 25,000 bioactive compounds, recombinant proteins, dye reagents, peptides and natural compounds for laboratory and scientific use.



• Bacterial Inhibitor
SPR206 acetate                  CAS No. : 2408422-41-1

SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L.

Compound Screening Libraries



50 specific libraries for high throughput screening (HTS) and high content screening (HCS). Optimized for drug screening and new indication research.

• Parasite Inhibitor
Purfalcamine                     CAS No. : 1038620-68-6

Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage.

Cell Signaling Pathway

• PARP Inhibitor
RBN012759                      CAS No. : 2360851-29-0

RBN012759 is a potent, selective and orally active inhibitor of PARP14, with an IC50 of <3 nM. RBN012759 displays 300-fold selectivity over the monoPARPs and 1000-fold selectivity over the polyPARPs. RBN012759 decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.

• Recent Publication Citing used MCE

1. Nature. 2020 Sep;585(7824):293-297.
2. Cancer Discov. 2020 Sep;10(9):1282-1295.
3. Cell Stem Cell. 2020 Sep 12;S1934-5909(20)30399-4. doi:
10. 1016/j.stem.2020.08.003.

• CXCR Agonist
PS372424 hydrochloride        CAS No. : 1596362-29-6

PS372424 hydrochloride, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 hydrochloride prevents human T-cell migration in a humanized model of arthritic inflammation.

• Epigenetic Reader Domain Inhibitor
NEO2734                                     CAS No. : 2081072-29-7

NEO2734 (EP31670) is an orally active dual p300/CBP and BET bromodomain selective inhibitor, with IC50 values of <30 nM for both p300/CBP and BET bromodomains. NEO2734 is active in SPOP mutant and wild-type prostate cancer.


Other New Products This Month

MCP110 (Ras) AG-494 (EGFR) SAG dihydrochloride (Smo)
VU-29 (mGluR) SR-717 (STING) Ilaprazole sodium (Proton Pump)
Mepazine (MALT1) PU02 (5-HT Receptor) SKF-83566 (Dopamine Receptor)
Avatrombopag (Integrin) …