DNA-encoded Library (DEL) DNA-encoded library (DEL) is a technology where each small molecule compound is linked to a unique DNA sequence at the DNA level, enabling DNA encoding similar to assigning a "barcode" to each molecule. DEL screening is a technique used in the early...
BioSynTech Malaysia Group (BSTM) is excited to announce our YEAR-END SALE on MCE Master of Bioactive Molecules products! 🎊 🗓️ Promotion Period: 1 September 2024 – 31 December 2024 🔖 Save 15% on a wide range of products with our special promo code: MCEYES15/2024! Check out our fantastic...
MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. • Over 100,000 bioactive molecules in stock • Target 10,000+ key proteins in 20+ signaling pathways • Quality reports (LC/MS,...
Customer Validation Covalent Drugs are a class of small molecule compounds that can covalently bind to specific target proteins, activating/inhibiting their corresponding signal pathways’ functions. They have a history of treating diseases for over a century, it could date back to the nonsteroidal anti-inflammatory drug aspirin...
What is Collagenase? Collagenase, also known as collagen proteinase, is isolated from Clostridium histolyticum, a spore-forming bacterium. It specifically recognizes the Pro-X-Gly-Pro sequence in collagen and cleaves the peptide bond between the neutral amino acid (X) and glycine (Gly) in that sequence. It is commonly used...
The 2024 AACR meeting wrapped up successfully in California, USA, showcasing the latest in innovative agents poised to enter clinical trials for cancer treatment. The spotlight was on key targets such as CDK, KRAS, and WRN, covering various types of cancers and therapeutic approaches. Dominating the...
Cell and Gene Therapy (CGT) With advancements in science and technology, the demand for precision in disease treatment is growing. Cell and Gene Therapies (CGT) were developed from years of research in life science. They use a wide range of molecular techniques to manipulate gene expression...
Oligonucleotides are specially designed sequences of nucleotides, which can be used as antisense oligonucleotides (ASOs), small interfering RNA (siRNA), microRNA (miRNA), aptamers, etc. Oligonucleotides can hybridize with target gene mRNA or pre-mRNA through complementary base pairing and modulate gene expression via various processes, including RNA interference...
Immune checkpoint (IC) proteins are key molecules that regulate the immune system by maintaining immune tolerance, determining the timing of the immune response, and controlling the intensity of the immune stress. Tumor cells exploit the immune checkpoint pathway as a major mechanism for immune escape,...
MedChemExpress (MCE) provides a wide range of life-science biochemicals, including more than 100,000 bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. If you need these products, please do not hesitate to contact us via CAS No.: 1421854-16-1 AC-186 Research Area: Estrogen Receptor/ERR/Neurological Disease • A...