22 Aug MCE | Death-inducing Pathways of Apoptosis
Apoptosis is programmed cell death, and abnormal apoptosis can lead to the development of diseases such as cancer, neurological disorders and autoimmune diseases[1]. Two main apoptosis pathways: Intrinsic Pathway The intrinsic pathway, also known as the Bcl-2 regulatory or mitochondrial pathway (Figure 1), is regulated by Bcl-2 family proteins, including pro-apoptotic proteins (Bid, Bax, Bak) and anti-apoptotic...