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  Cellular Senescence in Cornelia de Lange Syndrome : A Pharmacological Target? Tuesday, April 30, 2024 CEST 10:00 / IST 13:30 / JST & KST 17:00 Dr. Michel Pucéat • Research director at Inserm • Team leader and senior researcher In This Webinar, You Will Learn: • Programmed embryonic cell senescence in cardiac...

Tumor Immunotherapy During tumor development, immunotherapy inhibits highly expressed immune checkpoint molecules to restore T-cell recognition, thereby clearing or slowing tumor progression[1]. Immune Checkpoint Inhibitory Antibody Programmed cell death 1 (PD-1) is the T-cell immune checkpoint molecule of greatest interest. PD-1 or PD-L1 inhibitory antibodies upregulate T-cell activation and activate...

MedChemExpress (MCE) provides a wide range of life-science biochemicals, including more than 100,000 bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. CAS No.: 147030-48-6 KB130015 Research Area: Potassium Channel/Thyroid Hormone Receptor/Cardiovascular Disease • An orally active antiarrhythmic agent and a derivative of Amiodarone. • A hERG1 (Kv11.1)...

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MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. • Over 50,000 bioactive molecules in stock • Target 1000+ key proteins in 20+ signaling pathways • Quality reports (LC/MS,...

From the early smallpox virus to SARS-CoV-2, every pandemic of viral infections poses a severe threat to human health[1][2]. Due to the virus’s mutability, infectivity, and drug resistance, vaccines and antiviral drugs targeting the virus need to be continuously improved[3]. So far, many viral diseases...

Alzheimer's Disease (AD) is one of the most common forms of neurodegenerative disease characterized by progressive cognitive decline. The pathogenesis of AD is complex and remains elusive. The disease is marked by progressive deposition and accumulation of extracellular β-amyloid (Aβ), and aggregation of intracellular Tau...

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Seminar 1 30 Years in PI 3-kinase Research:Lessons Learned and Looking to the FutureWednesday, Nov. 15, 2023 9:00 CST / 15:00 GMT / 16:00 CETSpeaker: Bart Vanhaesebroeck Ph.D.•Professor of Cell Signalling at the UCL Cancer Institute•Elected member of EMBO and the UK Academy of Medical Sciences    About...