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Author: Editorial BSTM

Antibody-drug conjugates (ADCs) are a new class of anti-tumor drugs formed by coupling a specific monoclonal antibody to a cytotoxic drug through a linker. ADCs usually consist of a fully-humanized monoclonal antibody (mAb), a cytotoxic drug and a suitable linker. The primary role of the...

Angiogenesis in Cancer Angiogenesis, the physiological process of generating new blood vessels from existing ones, is a hallmark of cancer. Blood vessels are required for tumor growth for nutrition, oxygen, and excretion of metabolic waste and carbon dioxide [1,2]. Main Pro-angiogenic Regulators The angiogenic switch indicates a point...

With the advent of cancer immunotherapy and checkpoint inhibitors, significant progress has been made in targeting the host's autoimmune response as an anticancer therapeutic intervention, transforming the oncology immunity and cancer treatment field. The unofficial classification of tumors into "cold tumors" and "hot tumors" based on tumor immune...

Santa Cruz Biotechnology offers Annexin V Apoptosis Detection Kit for fluorometric detection of apoptosis. Kits include the reagents required for identifying a population of cells that have initiated apoptosis using a simple staining procedure and analysis by fluorescence microscopy or flow cytometry. Analysis of samples can...

20 µg, up to 20 transfectionsCRISPR/Cas9 Knockout (KO) Plasmids consist of a pool of three plasmids each encoding the Cas9 nuclease and a target-specific 20 nt guide RNA (gRNA) designed for maximum knockout efficiencygRNA sequences are derived from the GeCKO (v2) library and direct the...

Polyclonal antibodies can be used in a wide range of antibody-based assays. They are produced by injecting an immunogen into a host species (usually a rabbit). The serum can then be collected and purified. Purification can be done using physicochemical fractionation, class-specific affinity purification or...

MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use.• Over 50,000 bioactive molecules in stock • Target 1,000+ key proteins in 20+ signaling pathways • Quality...

Founded originally in Vancouver, British Columbia in 2006 by three enthusiastic entrepreneurs passionate about providing the best biological reagents worldwide, MyBiosource, Inc. was incorporated as a company with big visions. MyBioSource offers the widest selection of products at the best prices. If you need these...