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| MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. |
| • 200,000+ bioactive molecules |
| • Target 1,500+ key proteins across 20+ signaling pathways |
| • Quality reports (LC/MS, NMR and HPLC) for each product |
| • 1,000+ new biochemicals released monthly |
| • Data sheets with detailed biological information |
| • High purity at competitive prices |
| • Dispatched within 24 hours |
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CAS No.: 2489185-38-6
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Research Area: EGFR/Non-small Cell Lung Cancer (NSCLC)/Breast Cancer
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An orally active, brain-penetrant, highly selective and irreversible dual EGFR/HER2 inhibitor. |
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Targets exon 20 insertion (Ex20ins) mutations in EGFR and HER2. |
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Can be used in the research on NSCLC and
HER2-positive breast cancer. |
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Solubility: DMSO: 33.33 mg/mL (50.44 mM; Need ultrasonic)
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CAS No.: 300832-84-2
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Research Area: HCV Protease/Hepatitis C
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An orally active, reversible and selective HCV NS3 protease inhibitor with an IC50 of 3.0 nM. |
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Blocks NS3 protease-dependent polyprotein processing in HCV replicon-containing cells. |
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Can be used in the research on hepatitis C. |
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Solubility: DMSO: 12.5 mg/mL (16.13 mM; Need ultrasonic)
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CAS No.: 2082631-84-1
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Research Area: Peptide-Drug Conjugates (PDCs)/Folate Receptor
(FR)/TRP Channel/Solid Tumor
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A bi-specific ligand peptide-drug conjugate (PDC) targeting FRα and TRPV6 carrying MMAE as payload. |
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Can be used in the research on Platinum-resistant ovarian cancer (PROC), metastatic triple negative breast cancer (TNBC). |
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Solubility: DMSO: 25 mg/mL (7.33 mM; Need ultrasonic)
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| MedChemExpress Kits |
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| MedChemExpress (MCE) Organoid Induction Kit-PSC Induction Product Series is a professional induction culture system designed based on the principle of directed differentiation of pluripotent stem cells (PSC). It enables efficient and stable differentiation of human or animal-derived PSCs into organoids or specific lineage cells. This makes it ideal for research areas such as developmental biology, disease model creation, drug screening, and regenerative medicine. |
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| MedChemExpress Peptides |
| Product Name |
Description |
| Brevicidine TFA |
• An antimicrobial peptide against Gram-negative pathogens.
• Disrupt bacterial morphology by binding to membrane
lipopolysaccharides (LPS). |
| RP-182 acetate |
• A synthetic immunomodulatory peptide.
• Exerts anti-tumor effects by targeting the mannose
receptor CD206 (Kd = 8 μM). |
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| MedChemExpress Tissue Dissociation Enzymes |
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Tissue dissociation refers to the process by which enzymes effectively degrade
the extracellular matrix and intercellular adhesion structures, breaking down
biological tissues into individual cells or cell populations. Collagenase is
commonly used for tissue dissociation. |
| Product Name |
Application |
Collagenase, Type I
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Gingival epithelium, liver, lung, fat, breast tumors, and adrenals, etc. |
Collagenase, Type II
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Bone, heart, liver, thyroid, and salivary glands, etc. |
Collagenase, Type III
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Preparation of primary breast cells. |
Collagenase, Type IV
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Preparation of islet cells. |
Collagenase, Type V
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Preparation of islet cells by dissociating connective tissue into individual cells. |
Collagenase, Type VI
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Tumors, etc. |
Collagenase, Type VII
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Tumors, kidneys, brains, and lung epithelia. |
Collagenase, Type VIII
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lsolation of epididymal adipocytes and hepatocytes from rats. |
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| MedChemExpress Natural Products |
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Tripterygium wilfordii Hook F is a compound rich in terpenoids and
alkaloids, which has significant anti-inflammatory as well as immunosuppressive properties. It is widely used for studying autoimmune and inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and kidney disease. |
| Product Name |
Highlights |
Triptolide
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Exhibits immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. |
Celastrol
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A proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome. |
Triptonide
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A Wnt signaling inhibitor with immunosuppression,
anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects. |
Wilforlide A
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Has anti-inflammatory and immune suppressive effects. |
Demethylzeylasteral
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Exhibits functions such as anti-inflammatory, anti-tumor,
antifertility, estrogen metabolism regulation, immune suppression, and immune system regulation. |
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| MedChemExpress Compound Library |
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Provide professional compound library, serving cancer, immunity, metabolism and
other fields of research. |
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| MedChemExpress Isotope-labeled Compounds |
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| Latest Publications Citing Use of MCE Products |
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Nature.
2026 Feb;650(8100):251-260.
Nature.
2026 Jan;649(8098):1013-1021.
Science.
2026 Feb 5;391(6785):eadz4075.
Cell.
2026 Feb 5;189(3):922-938.e23. |
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