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| Stem cells (SCs) possess the remarkable ability to differentiate into various cell types and regenerate tissues. They are broadly classified into pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), and adult stem cells (ASCs). Among them, pluripotent stem cells, particularly iPSCs, hold significant potential in regenerative medicine and disease modeling, with fewer ethical concerns compared to ESCs[1][2]. |
The differentiation and maintenance of stem cells require a coordinated supply of growth factors, cytokines, and essential nutrients. The cytokines commonly used in stem cell culture fall primarily into two categories: the
transforming growth factor-β (TGF-β) superfamily and
colony-stimulating factors (CSFs). |
| References: |
[1] Development. 2013;140(12):2457-61.
[2] Vitam Horm. 2002:64:1-42. |
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MCE
One-Stop Screening Platform
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MCE
Stem Cell Related Compounds
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