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[MCE] New Bioactive Molecules for May 2025

[MCE] New Bioactive Molecules for May 2025


MedChemExpress - Master of Bioactive Molecules (Inhibitors. Screening Libraries. Proteins)
MedChemExpress offers a wide range of high quality research chemicals and biochemicals
including novel bioactive compounds, dye reagents, peptides and
natural compounds for laboratory and scientific use.
•  Over 100,000 bioactive molecules in stock
•  Target 10,000+ key proteins in 20+ signaling pathways
•  Quality reports (LC/MS, NMR and HPLC) for each product
•  Release more than 1,000 latest biochemicals per month
•  Data sheet with detailed biological information
•  High purity & competitive prices
•  Delivery within 24 hours

CAS No.: 2375591-69-6

Famlasertib

Target/Research Area: MAP4K/Amyotrophic Lateral Sclerosis

famlasertib structure
A brain-penetrant MAP4K inhibitor with an IC50 of 0.3 nM.
Shows motor neuron protection and anti-inflammatory
properties.
Can be used for the study of amyotrophic lateral
sclerosis (ALS)
.

Solubility: DMSO: 100 mg/mL (223.73 mM; Need ultrasonic)

CAS No.: 2798953-61-2

SCAL-255

Target/Research Area: Mitochondrial Metabolism/Cancer

scal-255 structure
A potent mitochondrial complex I (CI) inhibitor with an IC50 of 1.14 μM.
Blocks mitochondrial function, inhibits oxygen consumption rate (OCR), induces ROS production, and reduces mitochondrial membrane potential (MMP).
Can be used in the research of oxidative phosphorylation (OXPHOS)-dependent cancer.

Solubility: DMSO: 50 mg/mL (94.78 mM; Ultrasonic and warming and heat to 60°C)

CAS No.: 928122-40-1

GTx-027

Target/Research Area: Androgen Receptor/Breast Cancer/Stress Urinary Incontinence

gtx-027 structure
An orally active and non-steroidal selective
androgen receptor modulator (SARM).
Can be used in the research of breast cancer and
stress urinary incontinence (SUI).

Solubility: DMSO: 100 mg/mL (281.07 mM; Need ultrasonic)

MedChemExpress Natural Products
Lipids are a class of water-insoluble biomolecules, including compounds such as
fatty acids, glycerol, and phospholipids. Lipids play a crucial role in maintaining the health and normal functioning of living organisms, such as being the main components of cell membranes, providing energy reserves, regulating cell signaling, and participating in hormone synthesis.
Product Name Description
Ganglioside GQ1b (bovine) sodium
Promoting neurite outgrowth during early neuronal differentiation.
Sphingomyelin (d18:1/12:0)
Involved in lipid metabolism and has the potential to promote
neuronal cell growth. Playing a key role in the function and
development of the nervous system.
9-PAHPA
An endogenous lipid with antidiabetic and anti-inflammatory effects.
N-Palmitoyl-D-sphingomyelin
A naturally occurring sphingolipid that can be used in colorectal
cancer research.
9S-HODE
Main active derivative of Linoleic acid, which can reduce the
viability of HL-60 cells and induce apoptosis.
MedChemExpress Compound Library
Provide professional compound library, serving cancer, immunity, metabolism and
other fields of research.
Product Name Description
Mass Spectrometry Human Endogenous Metabolite Library
Contains 600+ mass spectrometry human endogenous metabolites that
can be used for metabolite identification and quantification,
functional cell detection and phenotypic screening of mass
spectrometry.
MedChemExpress Isotope-labeled Compounds








Latest Publications Citing Use of MCE Products
Covers of Recent Publications Nature.
2025 Apr;640(8057):249-257.
Science.
2025 Mar 7;387(6738):eadq2509.
Cancer Cell.
2025 Apr 14;43(4):740-756.e8.

Cell Signaling Pathway